Frequency and Risk Factor Analysis for Metronidazole-Associated Neurologic Adverse Events.

ABSTRACT:

Background

Little is known about the risk factors and frequency of metronidazole-associated neurological adverse events.

Objective

To investigate the risk factors and frequency of metronidazole-associated neurological adverse events.

Design

This retrospective study contained two parts. First, we investigated metronidazole treatment-associated neurologic adverse events by performing a population-based cohort study using the Korea Adverse Event Reporting System (KAERS) database from January 2011 to December 2020. Second, we conducted a matched case-control study based on a retrospective cohort of patients treated with metronidazole between January 2006 and July 2021 at a tertiary hospital in South Korea. The data analysis was performed from August 2021 to April 2022.

SUBMITTER: Lee SJ 

PROVIDER: S-EPMC11074090 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature