Naturally segregating genetic variants contribute to thermal tolerance in a Drosophila melanogaster model system.

ABSTRACT: Thermal tolerance is a fundamental physiological complex trait for survival in many species. For example, everyday tasks such as foraging, finding a mate, and avoiding predation are highly dependent on how well an organism can tolerate extreme temperatures. Understanding the general architecture of the natural variants within the genes that control this trait is of high importance if we want to better comprehend thermal physiology. Here, we take a multipronged approach to further dissect the genetic architecture that controls thermal tolerance in natural populations using the Drosophila Synthetic Population Resource as a model system. First, we used quantitative genetics and Quantitative Trait Loci mapping to identify major effect regions within the genome that influences thermal tolerance

SUBMITTER: Williams-Simon PA 

PROVIDER: S-EPMC11075556 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature