Impact of ^18FFDG-PET/CT and Laparoscopy in Staging of Locally Advanced Gastric Cancer: A Cost Analysis in the Prospective Multicenter PLASTIC-Study.

ABSTRACT:

Background

Unnecessary D2-gastrectomy and associated costs can be prevented after detecting non-curable gastric cancer, but impact of staging on treatment costs is unclear. This study determined the cost impact of ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (^18FFDG-PET/CT) and staging laparoscopy (SL) in gastric cancer staging.

Materials and methods

In this cost analysis, four staging strategies were modeled in a decision tree: (1) ^18FFDG-PET/CT first, then SL, (2) SL only, (3) ^18FFDG-PET/CT only, and (4) neither SL nor ^18FFDG-PET/CT. Costs were assessed on the basis of the prospective PLASTIC-study, which evaluated adding ^18FFDG-PET/CT and SL to staging advanced gastric cancer (cT3

SUBMITTER: de Jongh C 

PROVIDER: S-EPMC11076388 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature