Bacterial community analysis of the skin microbiota of cultured Chinese giant salamander infected with Ranavirus.

ABSTRACT: Skin microorganisms are an important component of host innate immunity and serve as the first line of defense against pathogenic infections. The relative abundance of bacterial species, microbial community assembly, and secretion of specific bacterial metabolites are closely associated with host health. In this study, we investigated the association between the skin microbiome and Ranavirus, and compared the bacterial community assemblage, alpha and beta diversity, and functional predictions of the skin bacterial assemblage in cultured healthy Chinese giant salamanders (Andrias davidianus) and individuals infected with Chinese giant salamander iridovirus (GSIV or ADRV). To achieve this, we employed 16S rRNA amplicon sequencing. The results identified Proteobacteria, Firmicute

SUBMITTER: Zhang H 

PROVIDER: S-EPMC11076746 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature