Conserved Genes in Highly Regenerative Metazoans Are Associated with Planarian Regeneration.

ABSTRACT: Metazoan species depict a wide spectrum of regeneration ability which calls into question the evolutionary origins of the underlying processes. Since species with high regeneration ability are widely distributed throughout metazoans, there is a possibility that the metazoan ancestor had an underlying common molecular mechanism. Early metazoans like sponges possess high regenerative ability, but, due to the large differences they have with Cnidaria and Bilateria regarding symmetry and neuronal systems, it can be inferred that this regenerative ability is different. We hypothesized that the last common ancestor of Cnidaria and Bilateria possessed remarkable regenerative ability which was lost during evolution. We separated Cnidaria and Bilateria into three classes possessing whole-body regen

SUBMITTER: Chereddy SCRR 

PROVIDER: S-EPMC11077316 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature