Biosynthetic gene clusters with biotechnological applications in novel Antarctic isolates from Actinomycetota.

ABSTRACT: Actinomycetota have been widely described as valuable sources for the acquisition of secondary metabolites. Most microbial metabolites are produced via metabolic pathways encoded by biosynthetic gene clusters (BGCs). Although many secondary metabolites are not essential for the survival of bacteria, they play an important role in their adaptation and interactions within microbial communities. This is how bacteria isolated from extreme environments such as Antarctica could facilitate the discovery of new BGCs with biotechnological potential. This study aimed to isolate rare Actinomycetota strains from Antarctic soil and sediment samples and identify their metabolic potential based on genome mining and exploration of biosynthetic gene clusters. To this end, the strains were sequenced using I

SUBMITTER: Bruna P 

PROVIDER: S-EPMC11078813 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature