Intraperitoneal chemotherapy for peritoneal metastases of gastric origin: a systematic review and meta-analysis.

ABSTRACT:

Background

Gastric cancer with peritoneal metastases is associated with a dismal prognosis. Normothermic catheter-based intraperitoneal chemotherapy and normothermic pressurized intraperitoneal aerosol chemotherapy (PIPAC) are methods to deliver chemotherapy intraperitoneally leading to higher intraperitoneal concentrations of cytotoxic drugs compared to intravenous administration. We reviewed the effectiveness and safety of different methods of palliative intraperitoneal chemotherapy.

Methods

Embase, MEDLINE, Web of Science and Cochrane were searched for articles studying the use of repeated administration of palliative intraperitoneal chemotherapy in patients with gastric cancer and peritoneal metastases, published up to January 2024. The primary outcome was overall surviv

SUBMITTER: Guchelaar NAD 

PROVIDER: S-EPMC11081074 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature