An atlas of spider development at single-cell resolution provides new insights into arthropod embryogenesis.

ABSTRACT: Spiders are a diverse order of chelicerates that diverged from other arthropods over 500 million years ago. Research on spider embryogenesis, particularly studies using the common house spider Parasteatoda tepidariorum, has made important contributions to understanding the evolution of animal development, including axis formation, segmentation, and patterning. However, we lack knowledge about the cells that build spider embryos, their gene expression profiles and fate. Single-cell transcriptomic analyses have been revolutionary in describing these complex landscapes of cellular genetics in a range of animals. Therefore, we carried out single-cell RNA sequencing of P. tepidariorum embryos at stages 7, 8 and 9, which encompass the establishment and patterning of the body plan, and initial di

SUBMITTER: Leite DJ 

PROVIDER: S-EPMC11083766 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature