Effect of 6,6'-Substituents on Bipyridine-Ligated Ni Catalysts for Cross-Electrophile Coupling.

ABSTRACT: A family of 4,4'-^tBu₂-2,2'-bipyridine (^tBubpy) ligands with substituents in either the 6-position, 4,4'-^tBu₂-6-Me-bpy (^tBubpy^Me), or 6 and 6'-positions, 4,4'-^tBu₂-6,6'-R₂-bpy (^tBubpy^R2; R = Me, ⁱPr, ^sBu, Ph, or Mes), was synthesized. These ligands were used to prepare Ni complexes in the 0, I, and II oxidation states. We observed that the substituents in the 6 and 6'-positions of the ^tBubpy ligand impact the properties of the Ni complexes. For example, bulkier substituents in the 6,6'-positions of ^tBubpy better stabilized (^tBubpy^R2)Ni^ICl species and resulted in cleaner reduction from

SUBMITTER: Huang H 

PROVIDER: S-EPMC11087080 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature