Motion correction of wide-detector 4DCT images for cardiac resynchronization therapy planning.

ABSTRACT:

Background

Lead placement at the latest mechanically activated left ventricle (LV) segments is strongly correlated with response to cardiac resynchronization therapy (CRT). We demonstrate the feasibility of a cardiac 4DCT motion correction algorithm (ResyncCT) in estimating LV mechanical activation for guiding lead placement in CRT.

Methods

Subjects with full cardiac cycle 4DCT images acquired using a wide-detector CT scanner for CRT planning/upgrade were included. 4DCT images exhibited motion artifact-induced false-dyssynchrony, hindering LV mechanical activation time estimation. Motion-corrupted images were processed with ResyncCT to yield motion-corrected images. Time to onset of shortening (TOS) was estimated in each of 72 endocardial segments. A false-dyssynchrony index

SUBMITTER: Manohar A 

PROVIDER: S-EPMC11087942 | biostudies-literature | 2024 Mar-Apr

REPOSITORIES: biostudies-literature