Dietary Super-Doses of Cholecalciferol Fed to Aged Laying Hens Illustrates Limitation of 24,25-Dihydroxycholecalciferol Conversion.

ABSTRACT:

Background

Older humans taking high concentrations of vitamin D₃ supplementation for a prolonged time may be at risk of vitamin D toxicity. It is unclear how dietary super-doses (10,000 times greater than the requirement) can affect vitamin D₃ status in aged animals. Aged laying hens could be a model to compare vitamin D₃ supplementation effects with women in peri- or postmenopausal stages of life.

Objectives

We investigated the dietary super-dose impacts of cholecalciferol (vitamin D₃) on vitamin D₃ status in aged laying hens in production.

Methods

Forty-eight 68-wk-old Hy-Line Brown laying hens were individually housed in cages with 8 hens per dietary treatment for 11 wk. Hens were randomly assigned to 1 of 6 tr

SUBMITTER: Warren MF 

PROVIDER: S-EPMC11088228 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature