Sporadic clone Escherichia coli ST615 as a vector and reservoir for dissemination of crucial antimicrobial resistance genes.

ABSTRACT: There is scarce information concerning the role of sporadic clones in the dissemination of antimicrobial resistance genes (ARGs) within the nosocomial niche. We confirmed that the clinical Escherichia coli M19736 ST615 strain, one of the first isolates of Latin America that harbors a plasmid with an mcr-1 gene, could receive crucial ARG by transformation and conjugation using as donors critical plasmids that harbor bla _CTX-M-15, bla _KPC-2, bla _NDM-5, bla _NDM-1, or aadB genes. Escherichia coli M19736 acquired bla _CTX-M-15, bla _KPC-2, bla _NDM-5, bla _NDM-1, and aadB genes, being only blaNDM-1 maintained at 100% on th

SUBMITTER: Carrera Paez LC 

PROVIDER: S-EPMC11089171 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature