Predictors of renal function deterioration at one year after off-clamp non-renorrhaphy partial nephrectomy.

ABSTRACT:

Background

Preservation of renal function is an important goal in renal cell carcinoma-related surgery. Although several case-dependent techniques for renal pedicle clamping and hemostasis have been used, their effects on long-term renal function are controversial.

Methods

The clinical records of 114 patients who underwent off-clamp non-renorrhaphy open partial nephrectomy at our hospital were retrospectively reviewed. Perioperative estimated glomerular filtration rate (eGFR) preservation was calculated, and predictors of eGFR decline 12 months post-surgery and overtime deterioration of renal function were identified using a multivariate regression analysis.

Results

The median patient age was 65 years, and the median tumor size was 27 mm. The mean eGFR preservation at

SUBMITTER: Nakamura M 

PROVIDER: S-EPMC11090305 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature