The association between pre-diagnostic levels of psychological distress and adverse effects after radical prostatectomy.

ABSTRACT:

Objectives

To prospectively analyse the associations between pre-diagnostic levels of anxiety and depression and patient-reported urinary and sexual adverse effects after radical prostatectomy in a population-based setting.

Patients and methods

In three Norwegian county hospitals, men referred with a suspicion of prostate cancer were asked to fill out a patient-reported outcome measurement (PROM) questionnaire prior to prostate biopsy. Those who later underwent radical prostatectomy were stratified into three distress groups according to their Hopkins Symptom Checklist 5-score. Additional PROM questionnaires, including the EPIC-26 to measure adverse effects, were collected at 6 and 12 months postoperatively. Multivariable mixed models were estimated and post hoc pairwise com

SUBMITTER: Nilsson R 

PROVIDER: S-EPMC11090769 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature