Childhood and adulthood passive and active smoking, and the ABO group as risk factors for pancreatic cancer in women.

ABSTRACT:

Objectives

Active smoking and the A blood group are associated with pancreatic adenocarcinoma (PC) risk. However, potential interactions between those risk factors and the role of passive smoking have been little investigated. We aimed to explore specific and joint associations of passive and active smoking, and effect modification by the ABO blood group in French women.

Methods

The study included 96,594 women from the E3N prospective cohort, mean age: 49 years (SD 6.7). Information on active and passive smoking was reported at inclusion and throughout follow-up. Cases were classified according to the International Classification of Diseases 10. Associations with passive and active smoking and effect modification by the ABO blood group were investigated with multivariable Co

SUBMITTER: Vedie AL 

PROVIDER: S-EPMC11091772 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature