Throat microbiota drives alterations in pulmonary alveolar microbiota in patients with septic ARDS.

ABSTRACT:

Objectives

The translocation of intestinal flora has been linked to the colonization of diverse and heavy lower respiratory flora in patients with septic ARDS, and is considered a critical prognostic factor for patients.

Methods

On the first and third days of ICU admission, BALF, throat swab, and anal swab were collected, resulting in a total of 288 samples. These samples were analyzed using 16S rRNA analysis and the traceability analysis of new generation technology.

Results

On the first day, among the top five microbiota species in abundance, four species were found to be identical in BALF and throat samples. Similarly, on the third day, three microbiota species were found to be identical in abundance in both BALF and throat samples. On the first day, 85.16% of micr

SUBMITTER: Li NN 

PROVIDER: S-EPMC11093027 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature