Regulation of early spermatogenesis in the giant prawn Macrobrachium rosenbergii by a GCL homolog†.

ABSTRACT: The germ cell-less gene is crucial for gonad development in various organisms. Early interventions in its expression suggested a regulatory role at the mitotic stages of spermatogenesis, and its early knockout resulted in complete sterility in Drosophila. Genomic and transcriptomic data available for the catadromous giant prawn Macrobrachium rosenbergii enabled the identification of a germ cell-less homolog for this species, which we termed MroGCL (mRNA accession number OQ533056). An open reading frame containing 494 amino acids and a typical evolutionarily conserved BTB/POZ domain suggests possible protein-protein interaction functions in keeping with the Drosophila germ cell-less protein. Genomic mapping of MroGCL showed a full length of 120 896 bases. Analysis of the temporal expression

SUBMITTER: Molcho J 

PROVIDER: S-EPMC11094379 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature