AnnoView enables large-scale analysis, comparison, and visualization of microbial gene neighborhoods.

ABSTRACT: The analysis and comparison of gene neighborhoods is a powerful approach for exploring microbial genome structure, function, and evolution. Although numerous tools exist for genome visualization and comparison, genome exploration across large genomic databases or user-generated datasets remains a challenge. Here, we introduce AnnoView, a web server designed for interactive exploration of gene neighborhoods across the bacterial and archaeal tree of life. Our server offers users the ability to identify, compare, and visualize gene neighborhoods of interest from 30 238 bacterial genomes and 1672 archaeal genomes, through integration with the comprehensive Genome Taxonomy Database and AnnoTree databases. Identified gene neighborhoods can be visualized using pre-computed functional annotations

SUBMITTER: Wei X 

PROVIDER: S-EPMC11094555 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature