Screening and identification of an aflatoxin B₁-degrading strain from the Qinghai-Tibet Plateau and biodegradation products analysis.

ABSTRACT: This research aimed to address the issue of aflatoxin B₁ (AFB₁) contamination, which posed severe health and economic consequences. This study involved exploring unique species resources in the Qinghai-Tibet Plateau, screening strains capable of degrading AFB₁. UPLC-Q-Orbitrap HRMS and NMR were employed to examine the degradation process and identify the structure of the degradation products. Results showed that Bacillus amyloliquefaciens YUAD7, isolated from yak dung in the Qinghai-Tibet Plateau, removed 91.7% of AFB₁ from TSB-AFB₁ medium with an AFB₁ concentration of 10 μg/mL (72 h, 37°C, pH 6.8) and over 85% of AFB₁ from real food samples at 10 μg/g (72 h, 37°C), exhibiting strong AFB₁ degrada

SUBMITTER: Tang Y 

PROVIDER: S-EPMC11094616 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature