Effects on Lung Tissue After Breast Cancer Radiation: Comparing Photon and Proton Therapies.

ABSTRACT:

Purpose

In breast cancer, improved treatment approaches that reduce injury to lung tissue and early diagnosis and intervention for lung toxicity are increasingly important in survivorship. The aims of this study are to (1) compare lung tissue radiographic changes in women treated with conventional photon radiation therapy and those treated with proton therapy (PT), (2) assess the volume of lung irradiated to 5 Gy (V5) and 20 Gy (V20) by treatment modality, and (3) quantify the effects of V5, V20, time, and smoking history on the severity of tissue radiographic changes.

Patients and methods

A prospective observational study of female breast cancer patients was conducted to monitor postradiation subclinical lung tissue radiographic changes. Repeated follow-up x-ray computed to

SUBMITTER: Siva Kumar S 

PROVIDER: S-EPMC11095095 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature