Epidemiological and health economic implications of symptom propagation in respiratory pathogens: A mathematical modelling investigation.

ABSTRACT:

Background

Respiratory pathogens inflict a substantial burden on public health and the economy. Although the severity of symptoms caused by these pathogens can vary from asymptomatic to fatal, the factors that determine symptom severity are not fully understood. Correlations in symptoms between infector-infectee pairs, for which evidence is accumulating, can generate large-scale clusters of severe infections that could be devastating to those most at risk, whilst also conceivably leading to chains of mild or asymptomatic infections that generate widespread immunity with minimal cost to public health. Although this effect could be harnessed to amplify the impact of interventions that reduce symptom severity, the mechanistic representation of symptom propagation within mathematical a

SUBMITTER: Asplin P 

PROVIDER: S-EPMC11095726 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature