Dual-Tuned Coaxial-Transmission-Line RF Coils for Hyperpolarized ¹³C and Deuterium ²H Metabolic MRS Imaging at Ultrahigh Fields.

ABSTRACT:

Objective

Information on the metabolism of tissues in healthy and diseased states plays a significant role in the detection and understanding of tumors, neurodegenerative diseases, diabetes, and other metabolic disorders. Hyperpolarized carbon-13 magnetic resonance imaging (¹³C-HPMRI) and deuterium metabolic imaging (²H-DMI) are two emerging X-nuclei used as practical imaging tools to investigate tissue metabolism. However due to their low gyromagnetic ratios (ɣ_13C = 10.7 MHz/T; ɣ_2H = 6.5 MHz/T) and natural abundance, such method required a sophisticated dual-tuned radiofrequency (RF) coil.

Methods

Here, we report a dual-tuned coaxial transmission line (CTL) RF coil agile for metabolite information operating at 7T with independent

SUBMITTER: Payne K 

PROVIDER: S-EPMC11095995 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature