Genome-wide detections for runs of homozygosity and selective signatures reveal novel candidate genes under domestication in chickens.

ABSTRACT:

Background

Indigenous chickens were developed through a combination of natural and artificial selection; essentially, changes in genomes led to the formation of these modern breeds via admixture events. However, their confusing genetic backgrounds include a genomic footprint regulating complex traits, which is not conducive to modern animal breeding.

Results

To better evaluate the candidate regions under domestication in indigenous chickens, we considered both runs of homozygosity (ROHs) and selective signatures in 13 indigenous chickens. The genomes of Silkie feather chickens presented the highest heterozygosity, whereas the highest inbreeding status and ROH number were found in Luhua chickens. Short ROH (< 1 Mb), were the principal type in all chickens. A total of 291 ROH

SUBMITTER: Tan X 

PROVIDER: S-EPMC11097469 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature