Expanding the clinical spectrum of anti-DPPX encephalitis: a multicenter retrospective study.

ABSTRACT:

Objective

Anti-dipeptidyl-peptidase-like protein-6 (DPPX) encephalitis is a rare autoimmune encephalitis, and clinical and experimental information regarding this disease is limited. We conducted this study to comprehensively describe the clinical characteristics, ancillary test results, neuroimaging results, and treatment response in a group of Chinese patients with anti-DPPX encephalitis for better understanding this disease.

Methods

We recruited 14 patients who tested positive for anti-DPPX antibodies in the serum and/or cerebrospinal fluid from 11 medical centers between March 2021 and June 2023. This retrospective study evaluated data on symptoms, autoantibody test, auxiliary examinations, treatments, and outcomes.

Results

The average age at diagnosis was 45.93 ±

SUBMITTER: Gao Y 

PROVIDER: S-EPMC11098017 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature