Resting state brain network segregation is associated with walking speed and working memory in older adults.

ABSTRACT: Older adults exhibit larger individual differences in walking ability and cognitive function than young adults. Characterizing intrinsic brain connectivity differences in older adults across a wide walking performance spectrum may provide insight into the mechanisms of functional decline in some older adults and resilience in others. Thus, the objectives of this study were to: (1) determine whether young adults and high- and low-functioning older adults show group differences in brain network segregation, and (2) determine whether network segregation is associated with working memory and walking function in these groups. The analysis included 21 young adults and 81 older adults. Older adults were further categorized according to their physical function using a standardized assessment; 54 o

SUBMITTER: Sato SD 

PROVIDER: S-EPMC11100712 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature