Neutrophil percentages in bronchoalveolar lavage fluid: Implications for diagnosing bacterial pneumonia in patients with immunocompromise and neutropenia.

ABSTRACT:

Rationale

Pneumonia is the most common infection in ICU patients and a leading cause for death. Assessment of bronchoalveolar lavage fluid (BALF) cellularity can aid in pneumonia diagnosis. Low percentages (<50%) of BALF neutrophils have a high negative predictive value for bacterial pneumonia in a general medical ICU population. The operating characteristics in patients with immunocompromise and neutropenia are less clear.

Objective

To compare BALF % neutrophils operating characteristics in patients with and without immunocompromise or neutropenia.

Methods

This was a single center observational cohort study. Patients were categorized into three groups: (1) patients with neutropenia, (2) patients with underlying immunocompromise, and (3) patients with neither. BAL-lev

SUBMITTER: Grudzinski KM 

PROVIDER: S-EPMC11100846 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature