Anti_spike and anti_nucleocapsid IgG responses to SARS-CoV-2 in children of Jordan.

ABSTRACT:

Background

It is proven that children have significantly milder COVID-19 disease compared to adults. Various immunological characteristics influence this age-related difference in protection against COVID-19. Pediatric COVID-19 in Jordan is extremely under reported.

Objectives

The primary goal of this work is to identify the anti_S and anti_N antibody responses in a random group of children in Jordan and compare it to that of naturally infected-unvaccinated adults.

Methods

151 unvaccinated children, 4 days to 18 years old, were screened for anti_S and anti_N antibodies. History of COVID-19 infection or exposure to infection and symptom severity were reported by parents on a special questionnaire.

Results

78.9 % and 65.3 % of participants were seropositive for a

SUBMITTER: Qaqish A 

PROVIDER: S-EPMC11101777 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature