Development and validation of the tic score for early detection of traumatic coagulopathy upon hospital admission: a cohort study.

ABSTRACT:

Background

Critically injured patients need rapid and appropriate hemostatic treatment, which requires prompt identification of trauma-induced coagulopathy (TIC) upon hospital admission. We developed and validated the performance of a clinical score based on prehospital resuscitation parameters and vital signs at hospital admission for early diagnosis of TIC.

Methods

The score was derived from a level-1 trauma center registry (training set). It was then validated on data from two other level-1 trauma centers: first on a trauma registry (retrospective validation set), and then on a prospective cohort (prospective validation set). TIC was defined as a PT_ratio > 1.2 at hospital admission. Prehospital (vital signs and resuscitation care) and admission data (vital sign

SUBMITTER: Brac L 

PROVIDER: S-EPMC11102139 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature