Atherosclerosis-related biomarker PABPC1 predicts pan-cancer events.

ABSTRACT:

Background

Atherosclerosis (AS) and tumours are the leading causes of death worldwide and share common risk factors, detection methods and molecular markers. Therefore, searching for serum markers shared by AS and tumours is beneficial to the early diagnosis of patients.

Methods

The sera of 23 patients with AS-related transient ischaemic attack were screened by serological identification of antigens through recombinant cDNA expression cloning (SEREX), and cDNA clones were identified. Pathway function enrichment analysis was performed on cDNA clones to identify their biological pathways and determine whether they were related to AS or tumours. Subsequently, gene-gene and protein-protein interactions were performed and AS-associated markers would be discovered. The expression

SUBMITTER: Lin M 

PROVIDER: S-EPMC11103157 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature