Impact of screening participation on modelled mortality benefits of a multi-cancer early detection test by socioeconomic group in England.

ABSTRACT:

Background

Cancer burden is higher and cancer screening participation is lower among individuals living in more socioeconomically deprived areas of England, contributing to worse health outcomes and shorter life expectancy. Owing to higher multi-cancer early detection (MCED) test sensitivity for poor-prognosis cancers and greater cancer burden in groups experiencing greater deprivation, MCED screening programmes may have greater relative benefits in these groups. We modelled potential differential benefits of MCED screening between deprivation groups in England at different levels of screening participation.

Methods

We applied the interception multi-cancer screening model to cancer incidence and survival data made available by the National Cancer Registration and Analysis Se

SUBMITTER: Smittenaar R 

PROVIDER: S-EPMC11103338 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature