Assessment of secular trends of three major gynecologic cancers burden and attributable risk factors from 1990 to 2019: an age period cohort analysis.

ABSTRACT:

Background

This study aims to assess the long-term trends in the burden of three major gynecologic cancers(GCs) stratified by social-demographic status across the world from 1990 to 2019. To assess the trends of risk factor attributed mortality, and to examine the specific effects of age, period, cohort behind them in different regions.

Methods

We extracted data on the mortality, disability-adjusted life years(DALYs), and age-standardized rates(ASRs) of cervical cancer(CC), uterine cancer(UC), and ovarian cancer(OC) related to risks from 1990 to 2019, as GCs burden measures. Age-period-cohort analysis was used to analyze trends in attributable mortality rates.

Results

The number of deaths and DALYs for CC, UC and OC increased since 1990 worldwide, while the ASDRs decr

SUBMITTER: Liu Y 

PROVIDER: S-EPMC11103856 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature