In vitro fertilization outcome based on the detailed early luteal phase trajectory of hormones: a prospective cohort study.

ABSTRACT:

Background

Ovarian stimulation and the use of human chorionic gonadotropin (hCG) for triggering oocyte maturation in women undergoing in vitro fertilisation (IVF) introduces several differences in luteal phase hormone levels compared with natural cycles that may negatively impact on endometrial receptivity and pregnancy rates after fresh embryo transfer. Exogenous luteal phase support is given to overcome these issues. The suitability of a pragmatic approach to luteal phase support is not known due to a lack of data on early phase luteal hormone levels and their association with fertility outcomes during IVF with fresh embryo transfer. This study determined early luteal phase profiles of serum progesterone, 17-hydroxyprogesterone and hCG, and associations between hormone levels/hor

SUBMITTER: N Vuong L 

PROVIDER: S-EPMC11103990 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature