Genome-wide association analysis uncovers rice blast resistance alleles of Ptr and Pia.

ABSTRACT: A critical step to maximize the usefulness of genome-wide association studies (GWAS) in plant breeding is the identification and validation of candidate genes underlying genetic associations. This is of particular importance in disease resistance breeding where allelic variants of resistance genes often confer resistance to distinct populations, or races, of a pathogen. Here, we perform a genome-wide association analysis of rice blast resistance in 500 genetically diverse rice accessions. To facilitate candidate gene identification, we produce de-novo genome assemblies of ten rice accessions with various rice blast resistance associations. These genome assemblies facilitate the identification and functional validation of novel alleles of the rice blast resistance genes Ptr and Pia. We unco

SUBMITTER: Greenwood JR 

PROVIDER: S-EPMC11106262 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature