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Single Nucleotide Polymorphisms in RUNX2 and BMP2 contributes to different vertical facial profile.


ABSTRACT: The vertical facial profile is a crucial factor for facial harmony with significant implications for both aesthetic satisfaction and orthodontic treatment planning. However, the role of single nucleotide polymorphisms (SNPs) in the development of vertical facial proportions is still poorly understood. This study aimed to investigate the potential impact of some SNPs in genes associated with craniofacial bone development on the establishment of different vertical facial profiles. Vertical facial profiles were assessed by two senior orthodontists through pre-treatment digital lateral cephalograms. The vertical facial profile type was determined by recommended measurement according to the American Board of Orthodontics. Healthy orthodontic patients were divided into the following groups: "Nor

SUBMITTER: Reis CLB 

PROVIDER: S-EPMC11108145 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature