Prognostication in Stargardt Disease Using Fundus Autofluorescence: Improving Patient Care.

ABSTRACT:

Purpose

To explore fundus autofluorescence (FAF) imaging as an alternative to electroretinography as a noninvasive, quick, and readily interpretable method to predict disease progression in Stargardt disease (STGD).

Design

Retrospective case series of patients who attended Moorfields Eye Hospital (London, United Kingdom).

Participants

Patients with STGD who met the following criteria were included: (1) biallelic disease-causing variants in ABCA4, (2) electroretinography testing performed in house with an unequivocal electroretinography group classification, and (3) ultrawidefield (UWF) FAF imaging performed up to 2 years before or after the electroretinography.

Methods

Patients were divided into 3 electroretinography groups based on retinal function and 3 FAF g

SUBMITTER: Daich Varela M 

PROVIDER: S-EPMC11108789 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature