Exercise-induced central and peripheral sympathetic activity in a community-based group of epilepsy patients differ from healthy controls.

ABSTRACT: Ictal and interictal activity within the autonomic nervous system is characterized by a sympathetic overshoot in people with epilepsy. This autonomic dysfunction is assumed to be driven by alterations in the central autonomic network. In this study, exercise-induced changes of the interrelation of central and peripheral autonomic activity in patients with epilepsy was assessed. 21 patients with epilepsy (16 seizure-free), and 21 healthy matched controls performed an exhaustive bicycle ergometer test. Immediately before and after the exercise test, resting state electroencephalography measurements (Brain Products GmbH, 128-channel actiCHamp) of 5 min were carried out to investigate functional connectivity assessed by phase locking value in source space for whole brain, central autonomic net

SUBMITTER: van den Bongard F 

PROVIDER: S-EPMC11108887 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature