Krill Oil for Knee Osteoarthritis: A Randomized Clinical Trial.

ABSTRACT:

Importance

Knee osteoarthritis is disabling, with few effective treatments. Preliminary evidence suggested that krill oil supplementation improved knee pain, but effects on knee osteoarthritis remain unclear.

Objective

To evaluate efficacy of krill oil supplementation, compared with placebo, on knee pain in people with knee osteoarthritis who have significant knee pain and effusion-synovitis.

Design, setting, and participants

Multicenter, randomized, double-blind, placebo-controlled clinical trial in 5 Australian cities. Participants with clinical knee osteoarthritis, significant knee pain, and effusion-synovitis on magnetic resonance imaging were enrolled from December 2016 to June 2019; final follow-up occurred on February 7, 2020.

Interventions

Participants

SUBMITTER: Laslett LL 

PROVIDER: S-EPMC11112499 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature