Antibiotics alter development and gene expression in the model cnidarian Nematostella vectensis.

ABSTRACT:

Background

Antibiotics are commonly used for controlling microbial growth in diseased organisms. However, antibiotic treatments during early developmental stages can have negative impacts on development and physiology that could offset the positive effects of reducing or eliminating pathogens. Similarly, antibiotics can shift the microbial community due to differential effectiveness on resistant and susceptible bacteria. Though antibiotic application does not typically result in mortality of marine invertebrates, little is known about the developmental and transcriptional effects. These sublethal effects could reduce the fitness of the host organism and lead to negative changes after removal of the antibiotics. Here, we quantify the impact of antibiotic treatment on development, ge

SUBMITTER: Krueger Q 

PROVIDER: S-EPMC11114123 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature