Body Composition in Advanced Non-Small Cell Lung Cancer Treated With Immunotherapy.

ABSTRACT:

Importance

The association between body composition (BC) and cancer outcomes is complex and incompletely understood. Previous research in non-small-cell lung cancer (NSCLC) has been limited to small, single-institution studies and yielded promising, albeit heterogeneous, results.

Objectives

To evaluate the association of BC with oncologic outcomes in patients receiving immunotherapy for advanced or metastatic NSCLC.

Design, setting, and participants

This comprehensive multicohort analysis included clinical data from cohorts receiving treatment at the Dana-Farber Brigham Cancer Center (DFBCC) who received immunotherapy given alone or in combination with chemotherapy and prospectively collected data from the phase 1/2 Study 1108 and the chemotherapy arm of the phase 3 M

SUBMITTER: Chaunzwa TL 

PROVIDER: S-EPMC11117154 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature