Specific Salivary Neuropeptides Shift Synchronously during Acute Stress in Fire Recruits.

ABSTRACT: Once thought of as an immune-privileged site, we now know that the nervous system communicates in a bidirectional manner with the immune system via the neuroimmune axis. Neuropeptides constitute a component of this axis, playing critical roles in the brain and periphery. The function of salivary neuropeptides in the acute stress response is not well understood. The purpose of this study is to investigate salivary neuropeptide levels during acute stress. Salivary samples were collected from fire recruits engaged in a stress training exercise previously shown to induce acute stress, at three separate timepoints during the exercise and levels of oxytocin, neurotensin, Substance P, α-MSH, and β-Endorphin were measured using the Human Neuropeptide 5-Plex Custom Assay Eve Technologies. All neuro

SUBMITTER: Ryznar R 

PROVIDER: S-EPMC11119501 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature