Probable Role of Type IV Pili of <i>Aeromonas hydrophila</i> in Human Pathogenicity.

ABSTRACT:

Background

Aeromonas hydrophila is a widely recognized broad-spectrum pathogen that primarily targets the gastrointestinal tract. Type IV pili (T4P) are proteinaceous nano-machines located on the bacterial cell surface, playing a crucial role in host colonization and infection. Regrettably, the T4P systems of A. hydrophila remain largely underexplored.

Methods

A. hydrophila genomes with complete genome assembly and annotation reports up to 31 March 2023, were obtained from the NCBI Genome database or KEGG genome database, followed by a global search for T4P secretion system genes. Protein sequences of these manually curetted genes were used as secondary quarry for Synteny analysis. Protein-protein interaction analysis was performed by string analysis and

SUBMITTER: Bhattacharyya A 

PROVIDER: S-EPMC11124393 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature