Visual field progression patterns in the ocular hypertension treatment study correspond to vulnerability regions of the disc.

ABSTRACT:

Objectives

To determine the locations on the 24-2 visual field (VF) testing grid that are most likely to progress in patients with ocular hypertension (OHTN). Based on a structural model of superior and inferior areas of relative vulnerability at the optic disc, we hypothesized that the nasal and paracentral regions are more prone to show a reduction in sensitivity.

Methods

Posthoc analysis of data collected in phases 1 and 2 of the Ocular Hypertension Treatment Study (OHTS). A pointwise analysis was applied to determine the progression patterns in the early and delayed treatment groups. Each group's progression rate and frequency were calculated for each of the 52 locations corresponding to the 24-2 VF strategy, using trend- and event-based analyses, respectively.

Result

SUBMITTER: Leshno A 

PROVIDER: S-EPMC11126578 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature