Comparative analysis, diversification, and functional validation of plant nucleotide-binding site domain genes.

ABSTRACT: Nucleotide-binding site (NBS) domain genes are one of the superfamily of resistance genes involved in plant responses to pathogens. The current study identified 12,820 NBS-domain-containing genes across 34 species covering from mosses to monocots and dicots. These identified genes are classified into 168 classes with several novel domain architecture patterns encompassing significant diversity among plant species. Several classical (NBS, NBS-LRR, TIR-NBS, TIR-NBS-LRR, etc.) and species-specific structural patterns (TIR-NBS-TIR-Cupin_1-Cupin_1, TIR-NBS-Prenyltransf, Sugar_tr-NBS etc.) were discovered. We observed 603 orthogroups (OGs) with some core (most common orthogroups; OG₀, OG₁, OG_2, etc.) and unique (highly specific to species; OG₈₀, OG

SUBMITTER: Hussain A 

PROVIDER: S-EPMC11126693 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature