Relative dispersion ratios following fecal microbiota transplant elucidate principles governing microbial migration dynamics.

ABSTRACT: Microorganisms frequently migrate from one ecosystem to another. Yet, despite the potential importance of this process in modulating the environment and the microbial ecosystem, our understanding of the fundamental forces that govern microbial dispersion is still lacking. Moreover, while theoretical models and in-vitro experiments have highlighted the contribution of species interactions to community assembly, identifying such interactions in vivo, specifically in communities as complex as the human gut, remains challenging. To address this gap, here we introduce a robust and rigorous computational framework, termed Relative Dispersion Ratio (RDR) analysis, and leverage data from well-characterized fecal microbiota transplant trials, to rigorously pinpoint dependencies between taxa during

SUBMITTER: Algavi YM 

PROVIDER: S-EPMC11126695 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature