Bioproduction of methylated phenylpropenes and isoeugenol in Escherichia coli.

ABSTRACT: Phenylpropenes are a class of natural products that are synthesised by a vast range of plant species and hold considerable promise in the flavour and fragrance industries. Many in vitro studies have been carried out to elucidate and characterise the enzymes responsible for the production of these volatile compounds. However, there is a scarcity of studies demonstrating the in vivo production of phenylpropenes in microbial cell factories. In this study, we engineered Escherichia coli to produce methylchavicol, methyleugenol and isoeugenol from their respective phenylacrylic acid precursors. We achieved this by extending and modifying a previously optimised heterologous pathway for the biosynthesis of chavicol and eugenol. We explored the potential of six S-adenos

SUBMITTER: Chua J 

PROVIDER: S-EPMC11127157 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature