Pelvic lymph node motion during cone-beam computed tomography guided stereotactic radiotherapy.

ABSTRACT:

Background and purpose

Stereotactic body radiotherapy (SBRT) is increasingly applied for pelvic lymph node recurrence. Thus far, knowledge on pelvic lymph node motion during CBCT-guided SBRT is lacking and the applied margins vary between institutions. This study evaluated pelvic lymph node motion during CBCT-guided SBRT and assessed the currently applied PTV margins of 3 and 5 mm.

Material and methods

In total, 45 pelvic lymph node metastases were included. One observer delineated 45 GTVs on planning CT, 224 GTVs on pre-fraction and 216 on post-fraction CBCT. The GTV centroid coordinates were derived from all images for inter- and intrafraction motion analysis. Additionally, we assessed the influence of treatment time and lesion location on lesion motion. The expected cover

SUBMITTER: Janssen J 

PROVIDER: S-EPMC11127188 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature