Long-term Remodeling Response in the Lamina Cribrosa Years after Intraocular Pressure Lowering by Suturelysis after Trabeculectomy.

ABSTRACT:

Objective

To measure the remodeling of the lamina cribrosa (LC) years after intraocular pressure (IOP) lowering by suturelysis.

Design

Cohort study.

Participants

Glaucoma patients were imaged 20 minutes after laser suturelysis after trabeculectomy surgery and at their follow-up appointment 1 to 4 years later (16 image pairs; 15 persons).

Intervention

Noninvasive OCT imaging of the eye.

Main outcome measures

Deformation calculated by correlating OCT scans of the LC immediately after IOP lowering by suturelysis and those acquired years later (defined as remodeling strain).

Results

The LC anterior border moved 60.9 ± 54.6 μm into the eye (P = 0.0007), and the LC exhibited regions of large local stretch in the anterior-posterior direction on long-term

SUBMITTER: Czerpak CA 

PROVIDER: S-EPMC11127792 | biostudies-literature | 2024 May-Jun

REPOSITORIES: biostudies-literature