Fluorescein-guided surgery in high-grade gliomas: focusing on the eloquent and deep-seated areas.

ABSTRACT:

Purpose

The vital function of eloquent and deep brain areas necessitates precise treatment for tumors located in these regions. Fluorescein-guided surgery (FGS) has been widely used for high-grade gliomas (HGGs) resection. Nevertheless, the safety and efficacy of utilizing this technique for resecting brain tumors located in eloquent and deep-seated areas remain uncertain. This study aims to assess the safety and extent of resection of HGGs in these challenging tumors with fluorescein and explore its impact on patient survival.

Methods

A retrospective analysis was conducted on the clinical and radiological data of 67 consecutive patients with eloquent or deep-seated HGGs who underwent surgery between January 2020 and June 2023. Lacroix functional location grade was used to d

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC11127876 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature