Fecal Coprococcus, hidden behind abdominal symptoms in patients with small intestinal bacterial overgrowth.

ABSTRACT:

Background

Small intestinal bacterial overgrowth (SIBO) is the presence of an abnormally excessive amount of bacterial colonization in the small bowel. Hydrogen and methane breath test has been widely applied as a non-invasive method for SIBO. However, the positive breath test representative of bacterial overgrowth could also be detected in asymptomatic individuals.

Methods

To explore the relationship between clinical symptoms and gut dysbiosis, and find potential fecal biomarkers for SIBO, we compared the microbial profiles between SIBO subjects with positive breath test but without abdominal symptoms (PBT) and healthy controls (HC) using 16S rRNA amplicon sequencing.

Results

Fecal samples were collected from 63 SIBO who complained of diarrhea, distension, constipati

SUBMITTER: Guo H 

PROVIDER: S-EPMC11128122 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature