Discovery of novel RNA viruses through analysis of fungi-associated next-generation sequencing data.

ABSTRACT:

Background

Like all other species, fungi are susceptible to infection by viruses. The diversity of fungal viruses has been rapidly expanding in recent years due to the availability of advanced sequencing technologies. However, compared to other virome studies, the research on fungi-associated viruses remains limited.

Results

In this study, we downloaded and analyzed over 200 public datasets from approximately 40 different Bioprojects to explore potential fungal-associated viral dark matter. A total of 12 novel viral sequences were identified, all of which are RNA viruses, with lengths ranging from 1,769 to 9,516 nucleotides. The amino acid sequence identity of all these viruses with any known virus is below 70%. Through phylogenetic analysis, these RNA viruses were classifie

SUBMITTER: Lu X 

PROVIDER: S-EPMC11129472 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature